10 Best Flea & Tick Treatments and Prevention for Dogs in 2025 – Reviews & Top Picks

10 Best Flea & Tick Treatments and Prevention for Dogs in 2025 – Reviews & Top Picks

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The info is present and up-to-date in accordance with the most recent veterinarian analysis.

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Applying flea drops to a dog with gloves

Applying flea drops to a dog with glovesDogs love being exterior to smell out scents and play a recreation of fetch within the yard. Unfortunately, our playful pooches can come into contact with nasty pests whereas exploring the wilderness. Flea and tick remedies and prevention assist cease your finest buddy from bringing again undesirable company together with their favourite ball.

These are available numerous choices, from shampoos and sprays to topical remedies, collars, and chewable tablets. We put collectively these evaluations that can assist you resolve which flea and tick therapy is the very best on your canine.

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The 10 Best Flea & Tick Treatments and Prevention for Dogs

1. Seresto Flea & Tick Collar for Dogs — Best Overall

Seresto Flea & Tick Collar for Dogs

Seresto Flea & Tick Collar for Dogs

Purpose: Prevention
Breed Size: Medium, massive, and large
Product Form: Collar
Life Stage: Puppy, grownup, senior

Recommended by veterinarians, the Seresto Flea & Tick Collar for Dogs is the very best total flea and tick therapy and prevention for canines. It’s designed to begin killing and repelling fleas and ticks inside 24–48 hours of becoming the collar in your canine. The collar is 27.5 inches lengthy to swimsuit medium, massive, and large breeds and is waterproof to stop the system from carrying off throughout wet walks or dips in ponds.

Along with working in opposition to fleas, ticks, and lice, the Seresto collar makes use of a long-lasting system to stop infestations for as much as 8 months.

While Seresto does manufacture flea collars for small canines, this one is designed for giant breeds and may be too massive on your pet.

  • Veterinarian really useful
  • Kills and repels fleas inside 24 hours
  • Kills and repels ticks inside 48 hours
  • 27.5-inch adjustable collar
  • Water-resistant
  • 8-month safety
  • Small canine breeds require a distinct product from the identical model

2. Richard’s Organics Flea & Tick Shampoo — Best Value

Richard's Organics Flea & Tick Shampoo

Richard's Organics Flea & Tick Shampoo

Purpose: Treatment
Breed Size: All
Product Form: Shampoo
Life Stage: Puppy, grownup, senior

Richard’s Organics Flea & Tick Shampoo is freed from parabens, synthetic colours, and fragrances. It accommodates 5 pure important oils, together with cedarwood oil, to moisturize and soothe irritated, flea-bitten pores and skin. As the very best flea and tick therapy and prevention for canines for the cash, it’s inexpensive and protected for canines 12 weeks and older.

Along with killing fleas and ticks, the shampoo works to repel mosquitos. It doesn’t intervene with topical flea and tick remedies, so you’ll be able to mix it together with your present flea safety regime.

Some customers have complained concerning the sturdy odor of this shampoo. Unfortunately, it will probably’t be shipped to California.

  • Cedarwood oil moisturizes pores and skin
  • Safe for canines 12 weeks and older
  • Five pure important oils
  • No synthetic colours or fragrances
  • Kills fleas, ticks, and repels mosquitos
  • Paraben-free
  • Doesn’t intervene with topical flea remedies
  • Can’t be shipped to California
  • Contains a powerful odor

3. Frontline Plus Flea & Tick Spot Treatment for Large Dogs — Premium Choice

Frontline Plus Flea & Tick Spot Treatment for Large Dogs

Frontline Plus Flea & Tick Spot Treatment for Large Dogs

Purpose: Prevention
Breed Size: Medium and huge
Product Form: Liquid
Life Stage: Puppy, grownup, senior

Formulated with fipronil and (s)-methoprene, Frontline Plus Flea & Tick Spot Treatment for Large Dogs works by disrupting the life cycle of your canine’s fleas. With the choice of a 6- or 8-month provide, you’ll be able to forestall infestations by killing present fleas, lice, and ticks and put an finish to larvae and eggs, too.

As this topical therapy is launched out of your canine’s oil glands, it presents waterproof safety and is protected from being washed away throughout your canine’s swim periods.

Frontline Plus should be re-applied as soon as a month, and the safety can grow to be ineffective in case you miss an software. It’s additionally really useful for canines within the prompt weight vary; a smaller or bigger breed would require a distinct system product with a selected dose of the system; they’ve a number of choices to cowl canines from 5 to 132 kilos

  • Waterproof safety
  • Kills grownup fleas, larvae, eggs, lice, and ticks
  • Disrupts the flea lifecycle
  • 6- or 8-month provide
  • Must be utilized as soon as a month
  • Recommended for canines within the talked about weight vary

4. K9 Advantix II Flea & Tick Spot Treatment for Dogs – Best for Puppies

K9 Advantix II Flea & Tick Spot Treatment for Dogs

K9 Advantix II Flea & Tick Spot Treatment for Dogs

Purpose: Prevention
Breed Size: Puppies, medium, massive, and large
Product Form: Liquid
Life Stage: Puppy, grownup, senior

Puppies additionally want safety in opposition to fleas and ticks, and K9 Advantix II Flea & Tick Spot Treatment for Dogs begins killing fleas, lice, ticks, and mosquitos inside 12 hours of making use of it in your canine. Recommended by veterinarians, the system offers waterproof safety in opposition to infestation and is on the market in 2-, 4-, or 6-month provides. Along with killing pests on contact, it additionally disrupts the flea lifecycle to assist cease infestations from persevering with.

This possibility is formulated for puppies 7 week of age and older and weighing 4 kilos or extra bigger canines ought to use a distinct therapy plan. Since K9 Advantix II is a topical therapy, it should be utilized as soon as a month to succeed in its most effectiveness, nevertheless it shouldn’t be used extra typically.

  • Starts working inside 12 hours
  • Waterproof
  • Disrupts the flea life cycle
  • Kills fleas, lice, ticks, and mosquitos
  • Available in 2-, 4-, or 6-month provides
  • Veterinarian really useful
  • Needs to be re-applied as soon as a month
  • Recommended for puppies 7 weeks of age and older and weighing  4lbs or extra
  • Smaller canines ought to use a distinct therapy

5. Veterinary Formula Clinical Care Flea & Tick Shampoo

Veterinary Formula Clinical Care Flea & Tick Shampoo

Veterinary Formula Clinical Care Flea & Tick Shampoo

Purpose: Treatment
Breed Size: All
Product Form: Shampoo
Life Stage: Puppy, grownup, senior

The Veterinary Formula Clinical Care Flea & Tick Shampoo fits canines 12 weeks and older. Available in 16-ounce or 1-gallon bottles, Veterinary Formula is protected for multi-pet households and presents 14 weeks of safety in opposition to infestations.

The 0.15% pyrethrins within the recipe kill fleas and ticks on contact, and the included aloe and lanolin soothe your pet’s flea-bitten and irritated pores and skin.

This shampoo shouldn’t be used on nursing puppies or pets youthful than 12 weeks or greater than as soon as per week. It additionally targets eggs or larvae and doesn’t interrupt the flea lifecycle, enabling eggs to hatch and delay infestations.

  • 14 weeks’ safety in opposition to fleas and ticks
  • Kills fleas and ticks on contact
  • Safe for multi-pet households
  • 16-ounce or 1-gallon bottles
  • Contains aloe and lanolin
  • Soothes irritated pores and skin
  • Unsuitable for puppies lower than 12 weeks outdated
  • Doesn’t kill flea eggs and larvae
  • Shouldn’t be used greater than as soon as per week

6. PetArmor Plus Flea & Tick Spot Treatment for Dogs

PetArmor Plus Flea & Tick Spot Treatment for Dogs

PetArmor Plus Flea & Tick Spot Treatment for Dogs

Purpose: Prevention
Breed Size: Large and large
Product Form: Liquid
Life Stage: Puppy, grownup, senior

Sold in a provide lasting both 3 or 6 months, PetArmor Plus Flea & Tick Spot Treatment for Dogs makes use of veterinarian-recommended substances to kill fleas, larvae, eggs, and ticks. The included fipronil and (s)-methoprene kill pests on contact and put an finish to the flea reproductive cycle to cease ongoing infestations, defending your canine for as much as 12 weeks. Like different topical remedies, this one is waterproof.

Although PetArmor presents 12 weeks of safety, your canine can nonetheless choose up fleas from their atmosphere. To correctly shield your finest buddy, you need to pair this with remedies on your residence and backyard. For the prevention therapy to be efficient, it needs to be utilized as soon as a month.

PetArmor Plus is on the market in 4 totally different packages for different-sized canines; the 5 to 22 kilos dose is appropriate for puppies in that weight vary of 8 weeks and older. They even have merchandise for canines starting from 23 to 44 kilos for medium canines, 45 to 88 kilos for giant canines, and 89 to 132 kilos for further massive breeds.

  • 12-week safety
  • Waterproof
  • Kills fleas, eggs, larvae, and ticks
  • Disrupts the flea life cycle
  • Available in 3- or 6-month provides
  • Uses veterinarian-recommended substances
  • Has to be re-applied as soon as a month
  • Dogs can nonetheless choose up fleas from the atmosphere
  • Should be partnered with flea remedies on your residence and backyard

7. TropiClean Maximum Strength Natural Flea & Tick Dog Shampoo

TropiClean Maximum Strength Natural Flea & Tick Dog Shampoo

TropiClean Maximum Strength Natural Flea & Tick Dog Shampoo

Purpose: Treatment
Breed Size: All
Product Form: Shampoo
Life Stage: Puppy, grownup, senior

The TropiClean Maximum Strength Natural Flea & Tick Dog Shampoo makes use of pure substances, like lemongrass and sesame oils, to guard your canine from fleas for as much as 7 days. Along with killing grownup fleas, TropiClean kills flea larvae, eggs, ticks, and mosquitos.

This shampoo is bought in 20-ounce or 2.5-gallon bottles for long-lasting use, even in multi-dog households. It’s additionally protected to make use of together with topical flea remedies.

Although TropiClean makes use of pure substances, it shouldn’t be used on puppies below 12 weeks outdated. Due to the flea safety counting on the product’s scent, the results don’t final so long as another choices. Also, the bottle has been recognized to interrupt open through the transport course of.

  • Kills fleas, larvae, eggs, ticks, and mosquitos
  • 7-day safety
  • Available in 20-ounce or 2.5-gallon bottles
  • Natural substances
  • Doesn’t intervene with topical remedies
  • Shouldn’t be used on puppies lower than 12 weeks outdated
  • The bottle can break throughout transport
  • The safety in opposition to pests doesn’t final lengthy

8. PetHonesty Flea & Tick Defense Soft Chews

PetHonesty Flea & Tick Defense Soft Chews

PetHonesty Flea & Tick Defense Soft Chews

Purpose: Prevention
Breed Size: All
Product Form: Soft chews
Life Stage: Adult

PetHonesty Flea & Tick Defense Soft Chews are a chemical-free strategy to maintain fleas, ticks, and mosquitos away out of your canine. The recipe makes use of pure substances (coconut oil, garlic, flaxseed, and brewer’s yeast) to guard in opposition to infestation and doesn’t comprise corn, wheat, soy, or GMOs. These substances, alongside the included omega fatty acids and nutritional vitamins, can strengthen your canine’s immune system to maintain your finest buddy wholesome.

Although the chews are hickory bacon flavored to encourage your canine’s urge for food, some fussy canines could dislike the style and refuse to eat them. Since they’re really useful for day by day, long-term use to be efficient, PetHonesty chews needs to be used alongside different flea and tick remedies.

  • Chemical-free
  • Repels fleas, ticks, and mosquitos
  • No corn, wheat, soy, or GMOs
  • Strengthens your canine’s immune system
  • Hickory bacon-flavored
  • Might require constant, long-term use to be efficient
  • Should be used alongside different flea and tick remedies
  • Fussier canines could dislike the flavour

9. Adams Topical Flea & Tick Spray for Dogs & Cats

Adams Plus Topical Flea & Tick Spray

Adams Plus Topical Flea & Tick Spray

Purpose: Treatment
Breed Size: All
Product Form: Spray
Life Stage: Adult

The Adams Topical Flea & Tick Spray for Dogs & Cats presents safety for multi-pet households with out worrying about mixing up topical remedies or frequent baths. This spray therapy is bought in 16- or 32-ounce bottles. Adams Spray helps kill fleas, larvae, eggs, and ticks and repels mosquitos for as much as 2 months after the preliminary software.

This product makes use of a powerful odor to repel mosquitos that some customers discover disagreeable. It’s really useful to be used on puppies older than ten weeks and may trigger stains if it comes into contact with furnishings, carpet, or clothes. The spray applicator can be simple to interrupt and doesn’t final lengthy.

  • Helps kill fleas, larvae, eggs, and ticks
  • Available in 16-ounce or 32-ounce bottles
  • Repels mosquitos
  • 2-month safety
  • Suitable for multi-pet households
  • Should be used on canines ten weeks or older
  • Might stain if it comes into contact with the carpet, furnishings, or clothes
  • Spray applicator breaks simply
  • Strong odor

10. NexGard Chew for Dogs

Nexgard Chew For Dogs

Nexgard Chew For Dogs

Purpose: Treatment and prevention
Breed Size: Medium and huge breeds
Product Form: Chews
Life Stage: Puppy, grownup, senior

Beef flavored to entice even the fussiest canine to eat it, the NexGard Chew for Dogs is an FDA-approved answer to tick and flea infestations. Veterinarians suggest the system to offer 30-day safety in opposition to fleas and ticks whereas remaining light sufficient for puppies 8 weeks and older.

Besides being costly, NexGuard has a protracted listing of potential negative effects and is just obtainable with a prescription from a veterinarian. The product shouldn’t be used greater than as soon as a month.

The chews themselves may additionally be too laborious for canines that discover it tough to chew or have lacking tooth. While they’re protected for canines, they’re poisonous to cats and needs to be used cautiously in multi-pet households.

  • Recommended by veterinarians
  • FDA permitted
  • Kills fleas and ticks
  • Beef taste
  • Suitable for puppies eight weeks and older
  • 30-day safety
  • Prescription solely
  • Can trigger severe negative effects
  • Expensive
  • Should solely be used as soon as a month
  • Chews may be too laborious for canines with lacking tooth
  • Toxic to cats

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Buyer’s Guide: How to Choose the Best Flea and Tick Treatment for Your Dog

Deciding that you just want your canine’s flea and tick therapy is just half the battle. From there, you must navigate the mismatch of collars, topical options, shampoos, and even oral drugs. They all have their execs and cons.

Your canine’s preferences, the severity of their infestation, and the way a lot time you must spare for repeated flea remedies are all issues to keep in mind when making your remaining selection. To assist you to take step one, we put collectively this information to point out you the distinction between every therapy and its advantages and drawbacks.

What to Consider When Buying a Flea and Tick Treatment for Your Dog

Before we get into the assorted remedies obtainable, just a few different issues might help make your remaining selection simpler.

Longevity

One of a very powerful issues to think about when buying a flea treatment is how lengthy it’ll final. Some remedies solely kill fleas on contact and should be repeated daily or so for the very best outcomes. This can eat into your already busy schedule.

Other remedies have a for much longer success charge at stopping infestations. While you must keep in mind to notice when to repeat the therapy, they’re much less time-consuming for individuals who aren’t at residence typically.

Waterproof

Dogs get moist. Even in the event that they do all the things to keep away from the hose and dreaded bathtub time, you’ll nonetheless discover them wading by means of muddy ponds, splashing in puddles, and racing about within the rain. Not all flea remedies are waterproof, and all these soggy actions can wash away the results, making your canine accessible to fleas once more.

Supply

Several flea remedies, like topical ointments, are available a small bulk provide. Since they’re designed for use as soon as a month, you’ll be able to typically purchase them in containers starting from one to 6 and even eight merchandise. A bigger provide can price extra upfront, however you received’t have to fret about shopping for extra of the identical model each month to maintain up together with your canine’s therapy.

That mentioned in case you discover that the therapy doesn’t work in addition to you’d hoped, a 6-month provide may go to waste if you find yourself not utilizing it.

man holding flea and tick medicine
Image By: Dmitriev Mikhail, Shutterstock

Treatment vs. Prevention

At first look, it may be simple to assume that therapy and prevention are the identical. While they’re typically mixed to make treating your canine for fleas simple, their intentions are totally different.

Treatment is the preliminary software. These merchandise are designed to kill fleas as quickly because the pests come into contact with them.

Prevention, however, is the lasting results formulated to maintain working for so long as potential. These merchandise soak up into your canine’s pores and skin or bloodstream and are launched slowly till it is advisable to reapply them.

For instance, a flea shampoo is technically a therapy. While it will probably use scents to push back or kill fleas for a short while after bathing, it’s formulated to kill the fleas on contact after you wash your canine. Topical therapy is extra of a prevention measure. It’ll kill fleas for so long as the chemical compounds are efficient.

Multi-pet Households

Many flea remedies formulated for canines are poisonous to different pets, like your cat. This isn’t an issue in case you maintain dog-only remedies away from their feline siblings. However, this may be simpler mentioned than achieved, particularly in case your pets take pleasure in snuggling up collectively for a nap.

It can be a difficulty in case you deal with each animals for fleas and ticks concurrently. If you rush by means of the applying or are a little bit drained, it’s simple to succeed in for the canine therapy as an alternative of the feline one.

To be protected, maintain the flea remedies on your pets separate, and attempt to maintain their therapy days separate, too. This will allow you to focus in your cats or canines with out risking a mix-up with their medicine. However, any time you aren’t certain, it’s at all times finest to seek the advice of your vet.

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What Types of Flea and Tick Treatment and Prevention Are There?

Now that what to think about when shopping for your canine a flea and tick therapy, listed below are the forms of remedies and prevention you should purchase on your canine. The finest one on your pooch may take some time, however with some effort, you’ll quickly have the best solution for your situation.

Collars

Collars are the way in which to go in case you want a long-lasting prevention measure. These adjustable, rubbery collars are coated in chemical compounds designed to kill fleas and ticks for as much as 8 months, supplied your canine wears one. For the new summery months, collars might be particularly helpful as a result of they supply constant safety even when your excitable canine launches themselves into each physique of water obtainable.

They typically match beneath your canine’s present collar, so that you don’t have to fret about ruining their avenue cred. Always go away room for 2 fingers when placing any kind of collar in your canine.

Woman wearing a collar for dog, kill and repel tick and flea
Image By: Chutima Chaochaiya, Shutterstock

Topical Solutions

Monthly remedies typically come as an answer that you just place evenly alongside your canine’s backbone. The chemical compounds used soak up into your canine’s pores and skin and sit of their oil glands to be launched slowly all through the month. Provided that you just maintain your canine away from water till it’s dry, most manufacturers are waterproof and supply safety even when your canine goes swimming.

Shampoos

If your canine enjoys bathtub time, buying flea shampoos could make bathing periods extra helpful. Not solely do they typically soothe irritated pores and skin, however they’re designed to kill fleas on contact. They typically use extra pure substances than different chemical flea remedies, too.

The draw back to shampoos is the frequency at which they’ve for use. Many pure shampoos solely final a couple of week earlier than needing to be reapplied. This can maintain your canine smelling recent but additionally strip their fur of wholesome oils.

Shampoos are additionally usually really useful for use alongside different flea remedies, like collars or topical options, for the very best outcomes.

Sprays

Although just like shampoos, flea sprays don’t lather and don’t must be washed away. They’re easy to use, requiring you simply to seize the bottle and spray your canine’s fur being conscious of their eyes. It’s finest to make use of these in locations that aren’t prone to staining, as some formulation can stain material.

Also, keep in mind to make sure the spray is appropriate to be used in your pet. Several sprays are solely designed for carpets, furnishings, or your backyard.

Chewable Tablets

Daily remedies can take the type of chewable tablets. They’re designed to be a one-off therapy to kill fleas shortly with out ready 1 or 2 days for a collar or topical answer to begin working.

Owner giving medicine in a pill to his dog
Image By: Creative Cat Studio, Shutterstock

How We Selected These Flea & Tick Treatments and Prevention for Dogs

This purchaser’s information was fastidiously crafted by our writers and editors in collaboration with our crew of in-house veterinarians. The flea & tick therapy and prevention for canines reviewed listed below are rated on a mix of things: model popularity, buyer evaluations throughout a number of stores, private expertise, and in some instances, suggestions from our personal canines! Together, we select and assessment solely the very best flea & tick therapy and prevention for canines obtainable, that can assist you take advantage of knowledgeable selections that foster the well-being of your furry buddies.

Why Trust Dogster?

Dogster has been a trusted model for canine house owners on-line since 2004, which suggests we’ve got a whole lot of expertise with flea & tick therapy and prevention for canines. We are a crew of passionate canine house owners who care about our pups as a lot as you do yours. We need the very best for each canine on the planet. Dogster’s writers, editors, and veterinarians are deeply invested within the well-being of our pets, and we imagine that each one pet house owners share this dedication to offering solely the best high quality services for our canines.

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Final Thoughts

Our evaluations coated the best flea and tick therapy and prevention for canines that can assist you and your favourite hound keep away from pest infestations. There is a variety of choices, together with the very best total possibility, the Seresto Flea & Tick Collar, with its 8-month-long safety. The budget-friendly selection, Richard’s Organics Flea & Tick Shampoo, is a pure therapy that moisturizes your canine’s pores and skin.

Whatever possibility you select, your canine will be pleased about the reduction from itchy flea infestations and creepy-crawly tick bites.

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